For those nerdlings among us who might be interested in whats was in that paper :
Effect of magnet applicators on niacinamide skin delivery and associated clinical improvements in barrier function Rosemarie Osborne, PhD, The Procter & Gamble Company, Mason, OH, United States; Peter Styczynski, PhD, The Procter & Gamble Company, Mason, OH, United States; Henrique Aveiro, PhD, The Procter & Gamble Company, West Chester, OH, United States; Heather Rocchetta, PhD, The Procter & Gamble Company, Mason, OH, United States; Larry Robinson, PhD, The Procter & Gamble Company, Cincinnati, OH, United States; Jim Li, PhD, The Procter & Gamble Company, Cincinnati, OH, United States; Debora Whittenbarger, MS, The Procter & Gamble Company, Cincinnati, OH, United States; Joseph Kaczvinsky, PhD, The Procter & Gamble Company, Cincinnati, OH, United States,
Magnetic-based applicators that induce diamagnetic repulsion and induced charge permeation have potential to improve skin benefits following application of skin care moisturizer formulations by increasing stratum corneum penetration. We evaluated the skin barrier response to a moisturizer formulation containing niacinamide when applied with an applicator designed with specifically constructed magnetic microarray. Clinical evaluation of the magnet applicator was conducted in a 4-week, randomized and controlled forearm study of 54 white women aged 30-60 years old, with a baseline TEWL range of stratum corneum barrier function from 6-16 g/m2 /hr. The results indicated a significant improvement in skin barrier as determined by TEWL with the niacinamide formulation applied with the magnet applicator as compared to either no treatment or treatment with the niacinamide formulation applied by finger. The product was well tolerated regardless of application method, as indicated by low visual redness and dryness expert grades. These findings suggest that magnet applicators provide clinical benefits and offer a new approach toward enhancing the delivery of skin care moisturizer formulations to the skin.
LINK:http://sci-hub.cc/10.1016/j.jaad.2016.02.062
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