What is your background with OPT? Where do you fit on the P3...

What is your background with OPT? Where do you fit on the P3 COAST success probability scale; 50, 60, 70, 80, or 90%?

I agree that the next six months will change everything; however, the next three months; and the readout; will determine whether the game is won or lost. If COAST fails, it would invalidate the science; and SHORE would be in serious doubt as well unless there was a really good explaination.

Obviously, I’m a big holder; so after research I have formed the belief ( strong beliefs loosly held) that both COAST and SHORE are extremely likely (80+%) to achieve clinical significance; even in subgroups.

Obviously with that dark side of a remote possibility of failure IMHO the only real question for the P3 science is; how many letters; 2,3,4,5,6+