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02/02/25
14:53
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Originally posted by FreeFromStyle:
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What is your background with OPT? Where do you fit on the P3 COAST success probability scale; 50, 60, 70, 80, or 90%? I agree that the next six months will change everything; however, the next three months; and the readout; will determine whether the game is won or lost. If COAST fails, it would invalidate the science; and SHORE would be in serious doubt as well unless there was a really good explaination. Obviously, I’m a big holder; so after research I have formed the belief ( strong beliefs loosly held) that both COAST and SHORE are extremely likely (80+%) to achieve clinical significance; even in subgroups. Obviously with that dark side of a remote possibility of failure IMHO the only real question for the P3 science is; how many letters; 2,3,4,5,6+
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Sorry for the ignorance - can you explain the 2 3 4 5 6+ part for me? Thanks in advance.