other current research

re financial report: the other smaller grants that PYC are benefiting from, show what other work is presently being carried out in-house.


One grant shows PYC are applying their EET to the discovery of antimicrobial peptides. Or in other words 'targeted intracellular antibiotics'.

The other grant shows work aimed at discovering cell-penetrating peptides that can modulate a class of intracellular proteins called G-coupled protein receptors (GCPRs); and new approaches to modulating GCPRs via their intracellular components.
In other words they are finding peptides that inhibit the buildup of amyloid plaques in the brain. These plaques are associated with Alzheimer's disease.

from the report:
"Research in Business Grant: Phylogica is benefiting from two grants totalling $100,000 from the Research in Business scheme – an initiative of Enterprise Connect and the Australian Government. The first grant was awarded directly to Telethon Institute for Kids in conjunction with Phylogica and will be used to explore novel applications of the Endosomal Escape Trap to discover antimicrobial peptides. The second grant was awarded to the University of Western Australia in conjunction with Phylogica. This grant subsidies the cost of Phylogica contracting the UWA-based scientist who will work on a project aimed at discovering cellpenetrating peptides that can modulate a class of intracellular proteins called G-coupled protein receptors (GCPRs); and new approaches to modulating GCPRs via their intracellular components."

For further info concerning PYC in-house check out pages 36-39 in the 'Scientific Supplement' of Telethon's 2013 Annual Report
Cheers
SoT