In some cases, side effects become so severe that Enhertu...

In some cases, side effects become so severe that Enhertu treatment needs to stop. This is referred to as “unacceptable toxicity.”

For example, if you develop lung problems* from Enhertu, your doctor may recommend pausing your treatment or decreasing your dose. If these problems don’t go away or they worsen, this may be considered an unacceptable toxicity. In other words, Enhertu may be harmful to your health.

If you develop an unacceptable toxicity from Enhertu, your doctor will likely recommend that you stop Enhertu treatment. They may suggest a different treatment for your cancer.

After having only a brief read this drug appears to be more toxic than the EFTI combo with similar results and in one of the subgroups inferior results.
Perhaps there’s a place for both types of treatments.