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Overwhelming efficacy - the stats required, page-404

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ddwn

12,523 Posts.

3391

13/09/20

19:32

Post #: 47304740
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Originally posted by Roy2U ↑

If the trial is stopped early at 60% (180 patients) for overwhelming efficacy, I estimate around 70 more patients would have been dosed or given placebo during the period between dosing the 180th patient and the decision to stop the trial.

My question to the experts on this board:

After the end of the trial, are the placebo patients immediately given the option of receiving Rem-L? If so, then we can't really get full trial data from the placebo patients in this last 70 patients dosed. Also, we would not be able to get 60 day data from some of the placebo patients in the first 180 patient group.

So, although we would eventually get full trial data on the half of approx 250 patients (approx 125) that received Rem-L, we may only get full trial data on a lot less of the placebo group (maybe 70-80?). Or have I got this all wrong?

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Lock it in!

Just like magic, we'll end up with having data for ~240 patients. Who would have thought?
Last edited by ddwn: 13/09/20

MSB Price at posting: $4.49 Sentiment: Buy Disclosure: Held
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