PAA 2022 , Human Trials , Covid , MND , Oncology , HVTL-1, K9 Phase III, page-14

First 14 Last

Share
Profile

Follow
adreamer

1,607 Posts.

1891

27/11/21

09:37

Post #: 57900053
Share

Originally posted by kpax: ↑

Hi All,

Well we have the WHO today, declare a new variant of concern "omicron".

The world market has taken notice. FTSE down 3.6% Oil down 13% Nasdaq and Dow Jones both 2% + down. Moderna 20% up.

So from a science perspective let's take a look at why.

Omicron is different to Delta in that it has two furin cleavage sites which increases its RNA ability to fuse with our ACE 2 receptors. In other words the protein spike on the virus has increased by a factor of possibly two. Making it more transmissible. Tom Peacock a Virologist at the Imperial College of London Department of Infections says " it is really awful". He also states that Omicron is genetically worse than any variant of Covid to date.

Ref : iflscience.com
New Covid-19 variant may be "worse than nearly anything else about " Warn Scientists. Nov 2021.

So how does this affect Pharmaust.
As most of we share holders know we have a significant royalty interest in Bromac which was on sold by Pharmaust to a private company.

Why is Bromac so special in relation to Omicron.

Remember you heard this on HC first !

We already have Monepantel that is already scientifically proven to interfere with the stage 3 of the Covid cell reproduction cycle once it is in the body. ( Covid 19 has four particular reproduction cycles). That is excellent.

But , what of Bromac. Well, it interferes with the ACE 2 receptors in our body to not link up with the virus once it enters our bodies. The ACE 2 receptors (or enzymes) are the first contact our cells have with Covid.

What is highly interesting to me. Is that Bromac and N Acetylcysteine have been studied to have a double impact on Covid. In that N Acetylcysteine is a potent mTOR inhibitor as well as a potent anti-inflammatory component thus negating the cytokine storm.

But the best part, is that Bromac can enter the double furin cleavage site of Omicron.

Have a look at this study to corroborate the above statements.

Ref : The Combination of Bromelain and Acetylcysteine ( Bromac) synergistically inactivates SARS-CoV-2.
Akhter/Morris 2021.

To be specific it's all about breaking down the glycans. Which Bromac does.

Are we looking at the demise of Covid ?
I will let you be the judge.

Read this study to see why the virus needs glycans.

Ref : Beyond Shielding : The Roles of Glycans in the SARS-CoV-2 Spike Protein. Caslalino et al . 2021

So is Acetylcysteine safe. You bet it is.
Is Bromac safe . Ditto.

Disclaimer : I take one medication per day . Yes, it's Acetylcysteine. Why as an anti oxidant and for its properties as an mTOR inhibitor as well as for its properties in relation to autophagy .
It is not a script based medicine and there is no patent involved.

Is this double combination the cure for Omicron ?

Some of the informed people who own this stock have told me personally that they would have no hesitation to take Monepantel if they acquired Covid 19. Soon some may also include Bromac in their medication repitoire.

Cheers All.

Expand

what is also helpful is it does neither MPL, N Acetylcysteine nor BroMac would need to be shipped in sub-zero environmental conditions.

Nice post mate.

Could this be a PAA second opportunity to join the COVID battle...? I guess time will tell.

PAA Price at posting: 9.8¢ Sentiment: Buy Disclosure: Held
13 Upvote

0 Great analysis

Reply

There are more pages in this discussion • 1,453 more messages in this thread...

First 14 Last

Add PAA (ASX) to my watchlist

(20min delay)
Last 32.0¢		Change 0.000(0.00%)		Mkt cap ! $126.1M

Open	High	Low	Value	Volume
0.0¢	0.0¢	0.0¢	$0	0

Buyers (Bids)

No.	Vol.	Price($)
1	20000	31.0¢

Sellers (Offers)

Price($)	Vol.	No.
33.5¢	41875	3

View Market Depth

No.	Vol.	Price($)
1	20000	0.310
2	45000	0.305
8	51966	0.300
1	20420	0.295
4	30922	0.290

Price($)	Vol.	No.
0.335	41875	3
0.340	96885	2
0.345	53348	4
0.350	3000	1
0.355	20000	1

Last trade - 09.21am 19/04/2024 (20 minute delay)


Last 31.0¢		Change 0.000 ( 0.58 %)
Open	High	Low	Volume
31.0¢	31.0¢	31.0¢	5000
Last updated 10.16am 19/04/2024 ?

PAA (ASX) Chart

Day chart unavailable

PAA 2022 , Human Trials , Covid , MND , Oncology , HVTL-1, K9 Phase III, page-14

Featured News

Recce Pharmaceuticals up 6% on new antibiotic production milestone

Market Update: Energy keeps light bright in a sea of red

Canada's Hillcrest Energy (CSE.HEAT) partners with BC's Powertech Labs

Crypto world awaits overnight Bitcoin halving event

Week 15 Wrap: USA uncertain, ECB shrugs at the Fed & gold, gold, gold

Buyers (Bids)

Sellers (Offers)

Featured News

PAA 2022 , Human Trials , Covid , MND , Oncology , HVTL-1, K9 Phase III, page-14

Featured News

Top Stories

Recce Pharmaceuticals up 6% on new antibiotic production milestone

Market Update: Energy keeps light bright in a sea of red

Canada's Hillcrest Energy (CSE.HEAT) partners with BC's Powertech Labs

Crypto world awaits overnight Bitcoin halving event

Week 15 Wrap: USA uncertain, ECB shrugs at the Fed & gold, gold, gold

Buyers (Bids)

Sellers (Offers)

Featured News