IMHO a big catalyst will be results of preclinical trials into other neurodegenerative indications.
At the moment we have all our eggs in the ALS basket which carries a fair amount of risk. If it looks like we can bring a second indication into play then that both increases our addressable market and also spreads the risk.
I'd imagine that strong preclinical results in a second indication could easily result in a doubling of the current share price.
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