PER - Megathread, page-240

Good post Sanders51
my take on the JG interview
Dmd

1)Chronic inflammation causes fibrosis/fatty infiltration
2)Corticosteroids administered to a child could only be active for a few years in the Ambulant space.. Causes major side effects.
3)Dystrophin loss causes inflammation
4)Research replacing dystrophen is not on the horizon .
5)Atl1102 tested on 20,000 gene transcripts with no off target problems
6)CD49d: Atl1102 lower doses0.5/1kg per week
other treatments 40/ per kg per week
a) lToxitity
b)Cost
7)Atl1102 anti inflammatory mechanism/
Fantastic combination therapy.
8) Clinicans will decide to continue using corticosteroids or Atl1102
9)Once successful in the non ambulant space Atl1102 could move to the Ambulant space.

So people hence the interest today $$