Remember the AKT pathway mentioned in the wikipedia extract...

Remember the AKT pathway mentioned in the wikipedia extract above, it does have something to do with insulin and diabetes 2.

In intracellular compartments, AKT converts glucose to glucose 6-phosphate by stimulating hexokinase. AKT regulates two processes by glycolysis Glucose 6-phosphate and glycogen synthase kinase 3 (GSK3) to produce cellular energy via glycolysis and promotes glycogen production by inhibiting FoxO proteins, particularly FoxO1, are the main target of AKT and affect energy homeostasis throughout body 31.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158718/#:~:text=AKT%20regulates%20glucose%20and%20lipid,also%20known%20as%20

Don't ask me what it means, but there definitely is a connection.