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That's just the specificity compared to the other known...

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    That's just the specificity compared to the other known demethylase protein (ALKBH5), and not all the other potential proteins in the body. Brequinar is also highly specific to FTO when compared to ALKBH5 (below), but still binds to DHODH with greater specificity than FTO.

    https://hotcopper.com.au/data/attachments/3553/3553697-e1d79ac3bc98b2760e6f384b89f859a0.jpg
 
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