Another partnership, pre-clinical (early Phase I). In PD-I blockade space.
https://www.bioworld.com/articles/5...as-cancer-tie-up-with-biond-valued-at-1b-plus
cancer prospect BND-22, a humanized IgG4 antagonist antibody targeting the Ig-like transcript 2 (ILT2) receptor in development for the treatment of solid tumors
From
- Israel-based Biotech ( so ... partnerships do happen for companies outside the US )
- IND filed for Phase I trial planned to start in 2021.
- USD $125M upfront
- + USD $1B in milestones
- Tiered double-digit royalties
https://www.prnewswire.com/news-rel...or-targeting-the-ilt2-receptor-301206200.html
Biond will lead the first-in-human, phase 1a study of BND-22, evaluating its safety and tolerability as a single agent and in combination with approved cancer therapeutics as well as exploring potential associations between BND-22 anti-tumor activity and select tumor and blood-based biomarkers; Sanofi will assume clinical development and commercialization responsibilities thereafter.
So the approach of identifying Biomarkers is similar to what RACE is doing for FTO. So I guess the above validates RACE's strategy.
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