RAC 1.27% $1.55 race oncology ltd

Pillar 1 - FTO (new thread), page-2062

  1. 1,983 Posts.
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    I wouldn't be too worried, as yet, @virtuozi

    CS2 has a higher probable IC50 than CS1 and going by prior P1 trial, the pharmokinetics of CS2 has a wide interpatient variability, which may make it unsuitable for treatment(but they assumed that the variability was non linear at higher doses, so if you can use CS2 at lower doses, it still may be OK). We won't know whether CS2 works or not until its treated as an FTO drug.

    This may mean they are first in clinic for FTO, but hopefully with all our abundant clinical trials, we are first in class(overall). And, additionally, considering UoC has come through and used it, you may wonder if the patent protection is also there.

    Ultimately, if CS2 is effective as an FTO drug in the clinic first, this should actually make us much more confident that Zantrene works. We should be hoping their trial is successful. Our hope is that our commercial expertise is sufficient that we still are first in class(not just best in class) at the finish line. The trial seems non commercial(from the article).

    CS2 prior P1 trial article: https://watermark.silverchair.com/cr0490164648.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAA9EwggPNBgkqhkiG9w0BBwagggO-MIIDugIBADCCA7MGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMXCW8x907lZ0IhIYeAgEQgIIDhKmTW5b6ah6k36_NF39MLW5EoxDX7w0PVwfYDc95mtZD6olzkZynF_7Tbf5lkKCIBMudqczn_5JX74VNYlUNa-AcnH5T6uo5X5ghLYhP1tocxvPiBmWt3DlG6wa0SA-5XBrzqgAk3RJrRibMQpJpP7LoTH67voW9pYgtiEwjlfmKf0Aba27Kn-WdS4P139fLF7M5H7QWbE-IJKvALyMyQA_CJhOQSQVus1_mFZuB1IR4qc2IsPLI9ACGbbbMG5f9Y3bevMa9nhoYnr-ANf997DJJo4PJ_FUiF2PM8w-Erbh30-gGcZs4iiMGNyi_fvcWN-gXNwbrjKg5FYulxR9bCd_c089O1CiQUfTaK3vaEAWHnWp3Z672Aed7ZXmhdQNkwKTvZq2knkh4cNyS1_fOeIJN7u_8s9A0u0hfRJCXoXfmXSiCYgQYqfyff2PxxBlUTDMtrMCqlHQdNprW71l2w8cvsyi4GlAsPXmsY4_t3TXjwhnQu5kB0rnoXNXuJy24Dm6dJcVTj_rovJSYPlf5XxfDrKHt6QYGGFDselTWZpdyg_dOx0dP06aFo9VH2aUR2YvPLmQ0_MVQpfN9nvXcZxJP4-5ZI3Y4ISiWnK282M6OoVo7wbvVMeZIOjOTDNOL2atKRwPLa6SQEDZ-f2m3ipXd4FQOLV2FHifREocD7z-8e_8fAh8s4ne1FUDUdzugBgFXiyO06yKuLWNUcz640xOQSCv8FvRuzGsIiYMrT27ZSaRU3oeuG9CaoKC8EttOQxR-vDL2gYySYSQT3SJHNEgRjRj7uQWgy574ZC3lry84db3LrcAQL6GLmIWbvzS51R9TqmZ3fDtzfvtQcsJjW6P48OSay081hRvvZOPDCJC10rr5u-GgXXfJQ7B3mvZx0WeSym4XiT2MRlNImCZ4hMBUTsVp-rOM4iOgyZX7CWmONjEcXrckt1HwhThII9pI75SqNQ8wNstMXpbayZ2fNCidd4ZVGVlNOKLvqvot7YnwX0bVRuIou6DCAsEtD4Ix92KpiAKmeAacnA0dEgZrki5t0Ft1YWyfcuvWAWUuZQ82X8S9HbKzZZ7AXMw-936H8-zO0ZZgpmQEpcg_TO47Fcn5xYjHx6b_ASalc7pGcb71OL8kkfzbmAwDqw8ctjODuoYkGdhhhiJXoMOAEE2j9eNuxERWzeQORyp11pdZeYrW4KUHMg
 
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