Slide 23 of the AGM shows that the aim for pillar one following preclinical activity is proof of concept trials.
Two key pieces of information are needed before we can accurately judge what those trials will be:
1) once we know what the FTO preclinical activity will be exactly (finding out very soon); and
2) if the preclinical trials are successful and if they are, in what way are they successful.
All IMO - DYOR
Pillar 1 - FTO (new thread), page-411
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