Thought I should add this to complete the section1.5. Skin Substitutes as an Alternative to Autologous Skin Transplantation
Over the years, a wide range of industrially manufactured skin substitutes have been established more or less successfully, so that a potpourri of purchasable skin substitutes are currently available on the market [3,68]. Each of these skin substitute materials plays a part in various research approaches and, in some cases, is also used in the clinical care of burn patients [69,70].Dermal skin substitutes can be broadly categorized as decellularized dermis derived from human or animal sources, artificially constructed scaffolds comprised of highly purified biomaterials or entirely synthetic polymers. In view of the fact that there are dozens of different commercially available skin substitute matrices on the market, only MatriDerm® (MedSkin Solutions Dr. Suwelack AG, Billerbeck, Germany) and NovoSorb® Biodegredable Temporising Matrix (BTM) (PolyMedics Innovations, Denkendorf, Germany) will be presented here as examples in detail, since they are currently standard in clinical use and show promising results. However, Table 1 provides an overview of other dermal skin substitutes of biological and synthetic origin currently available on the market.
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