polyprenol patents, page-3

Found a patent from Sultanov et al on a slightly different method used to extract polyprenols.

So looks like they can patent the method for a unique extract.


Method of processing wood greens by extraction. Roshchin, V. I.; Sultanov, V. S. (Russia). Russ. (2004), No pp. given. CODEN: RUXXE7 RU 2238291 C1 20041020 Patent written in Russian. Application: RU 2003-117227 20030606. Priority: . CAN 141:381269 AN 2004:894494 CAPLUS

Patent Family Information

Patent No. Kind Date Application No. Date
RU 2238291 C1 20041020 RU 2003-117227 20030606
AU 2004245874 A2 20041216 AU 2004-245874 20040427
AU 2004245874 A1 20041216
CA 2528242 A1 20041216 CA 2004-2528242 20040427
WO 2004108848 A1 20041216 WO 2004-RU162 20040427
W: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
RW: BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW, AM, AZ, BY, KG, KZ, MD, RU, TJ, TM, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR, BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG
DE 112004000993 T5 20061102 DE 2004-112004000993 20040427
US 2006198910 A1 20060907 US 2005-559114 20051202
LV 13463 B 20061220 LV 2006-2 20060106

Priority Application
RU 2003-117227 A 20030606
WO 2004-RU162 W 20040427


Abstract

Wood greens (leaves or needles with wood admixts.) are processed to recover valuable components by extn. with an org. solvent, followed by pptn. and filtration of waxes, alkali soln.-mediated sepn. of free acids from a soln. of extd. substances in a hydrocarbon solvent, sepn. of the neutralized soln. into a soln. of neutral substances in the hydrocarbon solvent and an aq. soln. of org. acid salts, acidification of the aq. soln. with an inorg. or org. acid, isolation of chlorophyllins and fatty and resin acids, sepn. of the diterpene acids and higher fatty acids, distn. of the solvent from the neutral substances, and sepn. of the neutral substances. The diterpene acids and higher fatty acids are treated with an alc. in the presence of sulfuric acid as a catalyst, followed by distg. off the alc. and neutralizing the diterpene acids and the catalyst using an inorg. base. The higher fatty acid esters are extd. with a hydrocarbon solvent, the aq. alkali soln. is acidified, and freed diterpene acids are extd. with a hydrocarbon solvent. The hydrocarbon solvent is evapd. to a concn. of diterpene acids of 30-50% to afford a rodent repellent. The neutral substances are successively extd. with acetone and a C1-C3-alc. at a ratio of the neutral substances to the extractant from 1:2 to 1:5. Treatment with acetone gives mixts. of higher fatty acid esters of triterpene alcs., sterins, and fatty alcs.; and an acetone-sol. residue. The residue is treated with an alc. to afford diterpene alcs. and alc.-insol. compds. The alc.-insol. compds. are sapond. with an alkali-alc. soln. to give a polyprenol-contg. mixt., which is subjected to chromatog. on silica gel at a substance/adsorbent ratio of 1:10 using hexane and hexane with 5-10% vol. of di-Et ether at an adsorbent/solvent ratio of 1:1 to isolate polyprenols.