Side effects associated with drugs are a well-known phenomena, and likely known to those who prepared the survey questionnaire.
Data can be adjusted to normalise for certain attributes that may otherwise bias results.
A single Phase 3 trial was authorised by the FDA following careful review of the proposal. It is likely that any data normalisation is well known to the FDA and agreed in advance of the commencement of the Phase 3 trial.
I would be very surprised - nay, shocked if the concerns you raise @hotcongo had any veracity.
Side effects associated with drugs are a well-known phenomena,...
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