https://www.ncbi.nlm.nih.gov/pubmed/30635844
Recent UK review of Recell which questions AVITAs "cost savings" model. Hardly compelling.
A lot of the massive invrease increase in outgoings is from the extra sales staff hired for the "launch" of the product. AVITA will have to be selling bucket loads of kits in order to cover the recurring staff costs.
"The manufacturer's clinical evidence submission included three papers and eight conference abstracts. The External Assessment Centre (EAC) excluded two of these and added seven abstracts. In general, the evidence did not fit the defined groups, but suggested that ReCell was clinically comparable to skin grafts for partial thickness burns; however, ReCell is not used in this way in the UK. The manufacturer submitted an economic model in which ReCell treatment of partial thickness burns reduced the requirement for later skin grafts. This indicated that ReCell alone was cost saving in comparison to conventional dressings. The EAC indicated that this model was clinically inappropriate, but data were not available to populate a new model. NICE Medical Technologies Guidance 21 recommended that additional research was needed to address the uncertainties regarding the potential benefits of ReCell."
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