I've been doing a little weekend research into other potential uses of EmtinB, which is derived from Metallothionein-II (MT-II). I came across an interesting paper from 2015 exploring the effect of MT-II on stroke. Here's my simplified & abbreviated summary of the full paper:
The authors found a significant reduction in cell death and neurological deficit in MT-II treated mice after middle cerebral artery occlusion (i.e. simulated stroke). It also improved survival of the mice, suppressed inflammatory cytokine induction in ischemic brain tissue, and protected primary neuronal cells against oxygen-glucose-deprivation in vitro.
Basically, MT-II has the potential to protect against brain injury in vitro and in vivo; potential being the operative word. I know it's a single paper from an average journal, but it's still interesting none-the-less! Perhaps more avenues for NSB to explore in the future.
(h)ttps://journals.plos.org/plosone/article?id=10.1371/journal.pone.0144035
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