Prana must be careful not to give away a fortune in cost saving by assuming there will be required a phase III trial. If we assume that, at a very high cost, and FDA accelerates PBT2 straight to market, it should not be Big Pharma winner take all. Such is the complexity of negotiations - you must consider all possibilities and get them in writing as to what will occur, or what is priced in, or how to do a deal where Prana gets more if there is no need for a phase III trial. That is my biggest concern in a partnership is to cut a deal assuming this enormous cost model presente by Big Pharma that may not transpire.
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