PYC pyc therapeutics limited

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Fat Harrys Cat

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17/11/24

20:52

Post #: 76646803
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Originally posted by Ladytradr: ↑

If we want to try and recollect some things

1. I have read in some older material that Sarepta were originally experimenting with CPP’s derived from viruses.
does anyone know if the CPP they used recently was derived from the same source?

PYC always goes to some effort to always use the expression ‘non viral’ CPP’s in the methodology they use.

I think that the FDA must be more comfortable with a nature derived protein fragment (I.e. not AI derived synthetic) than a nasty piece of a virus.

2. I think you may also find Sue Fletcher moved from Murdoch/Sarepta because she viewed PYC may have had a more diversified choice of CPP delivery mechanisms … as well as the Covid virus at the time had materially reduced the budgets she (and her team of young emerging genius scientists) would have staying at Murdoch University.
PYC now employs 64 from recollection

full credit must go to Rohan Hockings to identify and then execute quickly such a brilliant coupe

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I found an older paper/poster from the PYC group. It is:

Hall, Clinton et al Cold Spring Harbor Perspectives in Biology 8(7): a018069 (2016).

It states that the library is derived from “82 genomes and 118 synthetic viral genes.”

The genomes are from bacteria, archaea, fungi etc.
I guess the CCPs they currently use are not derived from the 118 synthetic viral genes.
I imagine that the vast bulk of the CCPs are from the bacterial, archaea etc genomes.

PYC Price at posting: 19.0¢ Sentiment: Buy Disclosure: Held
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PYC - General Discussion, page-624

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