TD1 50.0% 0.2¢ tali digital limited

Q&A video interview with Managing Director, Glenn Smith, page-14

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    Akili, is also currently developing app treating ADHD, still working towards FDA approval.

    Akili has raised ~USD$140m so far.

    Akili seems targeting higher ages.

    NHL, market cap A$33m does look very cheaper.

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    Merck, Amgen bump up Series B to $42.4M for Akili
    by Joseph Keenan |
    Jul 20, 2016 10:06am

    Akili Labs gets another infusion of Series B financing.
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    Akili Interactive Labs, the Boston-based startup developing nonpharmacological therapeutics for various cognitive disorders like autism and Alzheimer’s disease, got an $11.9 million boost in funding, raising its total Series B proceeds to $42.4 million.


    Joining existing Akili investors in the latest capital infusion are Merck Ventures and Amgen Ventures. The money will be used for continued product development and infrastructure as Akili products approach market launch, the company said.

    Akili’s device is based on the Project:EVO technology that the company in-licensed from the University of California, San Francisco, laboratory of Dr. Adam Gazzaley. The product is designed to directly target a person’s core neurological ability to process multiple streams of information. In so doing, the technology opens up a path that may improve attention, working memory and other executive functions at the same time it allows for monitoring and screening of a range of neurological and psychiatric disorders.


    The company has three versions of its clinical game technology, which will be a mobile-first technology for smartphones and mobile tablets.

    “There exists a tremendous opportunity to deliver medicine that is efficacious and addresses the needs for safe, non-pharmacological treatments in many neurological and mental health patient populations,” Eddie Martucci, co-founder and CEO of Akili, said in a statement.

    In addition to Merck and Amgen, Akili also has relationships with Pfizer ($PFE) and Shire Pharmaceuticals ($SHPG).

    Akili’s partnership with Pfizer is primarily focused on Alzheimer's with hope that the technology eventually will be able to identify a biomarker or cognitive endpoint for individuals at risk for Alzheimer's disease. The company also has partnered with the nonprofit Autism Speaks, and is conducting clinical trials of its cognitive assessment and personalized treatment video game.





    How a video game could treat ADHD
    JUNE 20, 2019 BY DANIELLE KIRSH LEAVE A COMMENT

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    Attention-deficit hyperactivity disorder makes it harder for people to pay attention and control impulsive behavior. It is one of the most common neurobehavioral disorders in children, according to the CDC. The treatment options for ADHD include behavioral therapy and medication intervention, but what if kids could use video games to treat the disorder? Akili Interactive, a digital therapeutics company, is combining digital therapeutics and video games to drive a therapeutic effect in people suffering from ADHD.

    The Boston-based company is making software to treat cognitive dysfunction in a number of disorders, but its flagship product is geared toward pediatric ADHD. Akili Interactive combines commercial gaming development, data science and neuroscience to create a platform for children to stay engaged with their therapy, a common issue with traditional ADHD treatment.

    “It doesn’t always feel like they’re taking medication when they’re engaging with our product,” Jason Trees, director of product management and head of R&D, said during a DeviceTalks Boston keynote address. “We know that we are producing therapeutic benefit, but it feels like a video game. As a result, we’ve made an effort to make it also appear like a video game.”

    Akili Interactive is a smartphone app that can be played on a tablet. Users can use their hands to tap and move the device using a built-in gyroscope and accelerometer. The game has characters and missions on the screen with a storyline to help pediatric ADHD users with retention. Akili Interactive is currently working through the details of which platforms to make the technology available through.

    “One of the core functions of our product is that it not only individualizes to whoever is playing it, but it can also constantly keep pushing you beyond your comfort zone essentially,” said Trees. “That’s part of what we think is the way in which our products work.”


    The digital therapeutics market is expected to be worth $9.1 billion by 2027 and the video game market will be worth $100 billion by 2022. A combination of the two niche industries allows people with ADHD to challenge themselves in a flexible and adaptable way, Trees said.

    Akili Interactive constantly measures and adapts to individuals to track progress and adjust the therapy as needed. Trees says the technology can be applicable in different countries and different cultures because it’s a video game.

    “I think that’s one thing that you do learn from the gaming industry is that games are pretty ubiquitously popular. That’s something that we’ve also strived to maintain – that we’re not narrow in a cultural sense,” Trees said.

    The company is currently running clinical trials to determine if the technology can work as a therapy for pediatric ADHD. It is also testing the technology in adjunct to stimulants. Akili Interactive plans to aim toward FDA approval and become a prescribed therapy in the future.
    Last edited by 8horse: 28/10/19
 
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