Question, page-8

This is why Isis is so important to Anp...also like Ive said time after time...and now Pharmas in numbers are interested in Anp pipeline...read the paragraph re safety and predictability.....

From Isis website:

Rational Design. Antisense drug discovery is more rational than any other type of drug discovery because:
We know the rules for creating antisense drugs. They bind to target RNA.
The building blocks of antisense technology are constant across all antisense drugs. It is the order of the building blocks that direct our drugs to a specific target.
The distribution and metabolism of antisense drugs are very similar from drug to drug, resulting in a common and often times, predictable, safety profile across all antisense drugs.