@Mason14 your thoughts are not a million miles away from my own.
I too am most excited about the FTO pillar. Amongst all the noise of recent days, DrT posted on the 31st March that '.... In some ways Bisantrene is more of a platform than a drug...'.
That comment really resonated with me.
Up until then I was certainly thinking of bisantrene as a drug (which of course it is), but if we consider bisantrene to be a 'platform', then I took that to be a reference to FTO inhibition. The thinking being that bisantrene's inhibitive effect on FTO will provide a potent weapon against a stubborn obstacle, creating the conditions necessary (i.e. 'a platform') across a range of cancers for existing chemotherapeutics to become all the more effective.
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