My man, how many times do you need to be shown the same thing before it sinks in?
I have linked this systematic review detailing all P1 trials conducted prior to 2020 for Oncolytic Viruses multiple times: Clinical Application of Oncolytic Viruses- A Systematic Review.pdf
I collated all the compounds that achieved a response from the phase 1 section alongside CF33. Plenty of OV therapies are contained within that list achieved a CR and none of them have been successful commercially. Even CG0070 is still in clinical development after a near 50% CR rate in Bladder cancer at P1 - Why? Because the market is extremely competitive.
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