PYC pyc therapeutics limited

re: pyc - investor presentation - july 2012, page-4

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    re: pyc - investor presentation - july 2012 If you look on slide 40 beside "Peptide drugs against intractable extracellular targets" it has under "In-House Activities & Partnerships"...

    Developing new screening assays against high-value GPCRs

    I contacted Nick Woolf to ask if he could give me a short description of what GPCR targeted drugs are and Phylogica's role with them are and here's his reply....

    G protein-coupled receptor

    GPCR-targeted drugs are one the largest drug classes. These receptors are key regulators of cell biology. Some of the high-value GPCRs have been challenging to hit with conventional small molecule or antibody drugs because of their complex biological shapes. We can tackle these ones with our Phylomers.

    http://en.wikipedia.org/wiki/G_protein-coupled_receptor

    Number of deal discussions to date in this space = 8.

    Phylogica just need one of their Phylomers in the hands of one of their partners, or indeed in their own hands, to show proof of concept (even preclinical) against a high-value challenging target. Then they will be taken out.

    Regards,
    Tony

 
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