New Antivirals Needed Influenza viruses can develop resistance to antivirals over time. New antivirals will be needed in the event H5N1 develops resistance to Tamiflu or Relenza. We are committing $200 million to the development of additional antivirals. HHS expects to request formal proposals later this spring and to award contracts for the advanced development of promising antivirals by September 2006. It is not enough to stockpile antivirals; there needs to be a plan to distribute them. HHS is discussing with the states whether the antivirals should be centrally located or warehoused locally. To receive funding, states are being required to develop distribution plans now, so that if a pandemic erupts, it will be clear where the drugs are to go and how they will get there. In addition to stockpiling antivirals, $162 million will be used to procure essential medical supplies for a pandemic.
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