I'd love to know why Janssen walked but of course we wont be privy to this & maybe even the company might not know clearly. If I was going to take a punt i'd say it comes back to efficiency or lack of but what would I know, just gut. Also strange that the decision was made the day after TIDES presentation or maybe even same day really with time zones - was just a matter of face to face convenience being in the US already ?
As for TIDE's schedule these presentations looked interesting, on face value only - no idea of actual content & the two Arrowhead ones below. Would like to have known what Sawyer had to say in his Featured Presentations.
Direct Selection of Macrocyclic Peptides Targeting Intracellular Protein-Protein Interactions Kris Josephson, Ph.D., Director of Molecular Biology, Ra Pharmaceuticals, Inc.
Delivery of Proteins into Live Human Cells: Virus-inspired Strategies and Therapeutic Opportunities Jean-Philippe Pellois, Ph.D., Associate Professor, Department of Biochemistry and Biophysics, Texas A&M University
Next Generation Dynamic Polyconjugates for siRNA Delivery in vivo Aaron M. Almeida, Ph.D., Senior Scientist, Chemistry, Arrowhead Research Corporation
Unpublished Data Using Endosomal Escape Agents for siRNA Delivery in vivo David L. Lewis, Ph.D., Chief Scientific Officer, Arrowhead Research Corporation
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(20min delay)