BTA 0.00% 57.0¢ biota holdings limited

recent fda solicitation for h5n1 study

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    Commencement of Replenishment of Govt Stockpiles of Oseltamivir and Zanamivir are just around the corner - the results of this study if timely could be a leg up for GSK and BTA royalties

    https://www.fbo.gov/index?s=opportunity&mode=form&id=b9a02a0baa01681decceb5308f8de008&tab=core&_cview=1

    Background
    Human infections with avian influenza A (H5N1) are associated with high mortality. As of July 5, 2010 there had been 500 cases and 296 fatalities. The influenza virus readily undergoes mutation and re-assortment, and there are concerns that an H5N1 variant could be responsible for a future pandemic. The influenza neuraminidase inhibitors Zanamivir and Oseltamivir are approved for the treatment and prophylaxis of influenza. Oseltamivir is being used to treat H5N1 infections and a case has been made supporting the use of Zanamivir also; however, there are no reports for the latter. Despite treatments with early use of oseltamivir combined with supportive care as suggested by WHO, 30% to 80% of hospitalized patients with H5N1 influenza have died, and an oseltamivir-resistant virus has developed in some patients.


 
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