There would be a pooled treatment vs placebo analysis. It's common for follow up periods to be different for trials as recruitment can easily stretch 2-3 years for larger trials.
Pooled analysis also increases power and so would the increased treatment time in the first cohorts as hopefully variability in placebo responses would dampen over time given as you know the natural history of the disease.
We are all locked in now so hopefully it works for us and patients as neurology has traditionally been a speciality where you can diagnosis anything and cure nothing. The brain really is very poorly understood at a fundamental level, its complexity is out of my league at least.
LCT Price at posting:
20.5¢ Sentiment: Hold Disclosure: Held
