https://jvi.asm.org/content/jvi/early/2018/01/11/JVI.02118-17.full.pdf
Page 18
Human resting CD4+ T cells from hu-NSG mice on suppressive cART contain replication-competent HIV
Although prolonged cART therapy suppresses HIV replication below the detectable level, HIV persists as a transcriptionally inactive provirus in resting memory CD4+ T cells; this so-called latent reservoir has a long half-life, and prevents HIV eradication by cART alone (8). HIV latency may be reversed by inducing resting CD4+ T cell activation and subsequent release of infectious viruses capable of new infection
Acknowledgments
Funding & Support: This work was supported by the National Institutes of Health [grant numbers R01AI29329 to J.J.R. and R01AI42552 and R01HL07470 to J.J.R. and J.C.B] and National Cancer Institute of the National Institutes of Health [grant number P30CA033572 to support City of Hope Integrative Genomics, Analytical Pharmacology, and Analytical Cytometry Cores]. Funding for open access charge: National Institutes of Health. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. The following reagents were obtained through the NIH AIDS Research and Reference Reagent Program, Division of AIDS, NIAID, NIH: HIV BaL virus.
Bit-009 claims we clear HIV in this latent reservoir, which would give any potential Pharmer a superior treatment plan!!! $10 billion giving the platform away…..
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