If one looks at the dosages reported, there is an order of magnitude in difference between PAR's treatment (iPPS) vs oral treatment for bowel inflammation. iPPS in BML treatment published by PAR is 2mg/kg x 12 (2 injections per week over a 6 week period) if the patient weighed 100kg is equal to 2.4g per year.
For bowel treatment the numbers mentioned for chronic use were 500g and more than 1500g over 15 years. So 33g and more than 100g per year. This is 14 times more or more than 42 times more than the iPPS treatment dosage per year. I doubt if the toxicity levels would be the same. As with all medications there are expected to be side effects. Just not sure if this would really be an issue for iPPS treatment due to dosage.
I currently hold PAR. Would be looking to buy more if it drops much lower.
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