Thanks Chels, it will be very interesting to read the MPS VI trial which is blinded and up against placebo. The numbers are larger there so that also will be good to see. Specially from a pain front, it really is the only viable option apart from NSAIDS which have many problems if used on a daily basis over a longer period of time.
I think there will be a big case once approved to start iPPS early in life for these guys...this also is why the Brazil study (MPS VI) is important as it breaks the cohort by age stratum as well.
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