research reports and media, page-379

Rennie had a interview with Alan Kohler, who also has knee problems.
Rennie took Kohler through what we know, also emphasizing that a lot of AFL users were less than 30 years old.
He also did a plug for approaching local doctors on basis that all other medications had failed, and there was a case that they could make for TGA special access for which PAR make no charge.
He also mentioned that Bene Pharma are the only FDA approved producer, and they have that 20 years supply agreement.
at tail end of interview...
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The actual compound is extracted from the bark of the European beech tree and that process of extraction is a very difficult one because there are many different molecules in the organic material. Extracting just the Pentosan, which is a five-sugar polymer, which is the backbone to the drug, is part of the art that the Germans have perfected.
....
If you just take European beech tree and try and extract out Pentosan, you will get a whole range of other compounds and those compounds may or may not be beneficial for the patient. They may have deleterious effects. Making sure that you only get the Pentosan is very important and I think the Germans have definitely perfected that.
And then you add Polysulfate and sodium to it,...
You get the Pentosan from the beech tree, it goes through a synthetic process of adding the Polysulfates and then extracting the sodium salt from that and then producing the very bottom of the process, Pentosan Polysulfate.
"