right place and time, page-5

Passage form previous post.
"The following study that indicates that chemos given after vaccines, with the possible exception of doxorubicim, may eliminate vaccine effectiveness, and further supported by DNDN’s 9901 Fisher Exact p value for patients receiving chemo post trial, and more recent studies showing that while chemos may reduce regulatory T cells (good), they may also eliminate the memory T cells primed by vaccines that give some long-term protection against their targeted marker and associated markers through epitope spreading / antigen cascade. Review Articles Leveraging the Activity of Tumor Vaccines with Cytotoxic Chemotherapy Leisha A. Emen and Elizabeth M. Jaffe Departments of Oncology, Immunology, Pathology, and Pharmacology, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, Maryland Cancer Research 65, 8059-8064, September 15, 2005 http://cancerres.aacrjournals.org/cgi/content/abstract/65/18/8059"