Rough thoughts in questions - help yourselves

But I threw together some thoughts in about 10 mins or so -- (probably 30 now with posting to this forum)

Questions for KK tomorrow - at present I'm not planning to ask them - others are welcome to if they wish

Phase 2 GVHD

- Is there anyreason why patient’s treated aren’t being reported as a number,1^st , 2^nd, 3^rd etc rather than as apercentage (about 5%).

- Has the treatmentarm to control arm ratio been fixed? (ie 40 to treatment arm 20 tocontrol for a 2 to 1 ration or 30 to treatment arm 30 to control fora 1 to 1 ratio).

If not why not?

Is there any chancethat Cynata will need to raise funds to complete phase 2 in GVHD –or have the expenses for that discretionary undertaking by themanagement team already been fully paid for?

Recruiting – whyspend money recruiting a person to look at partnerships when thesubstantive value adding data that partners would be interested in(results from clinical trials) is still being generated? Isn’t thatpremature? Isn't it unfair to put a new hire into the money at 29cents if trial results come in that lift CYP above that through no work (on those trials) by the new hire?

MSB as a competitor

If MSB is granted aBLA for GVHD – what impact does Kilian see that having on orphandrug designation funding in the US if any – for instance does hethink it would be deemed the same drug by the FDA?

Does MSB’s patentgranted November 2023 in the US – entitled Mesenchymal Stem CellsExpressing TNF-alpha receptors constitute a problem for Cynata?

In the advent ofpatent offices granting patents too broadly to competitors doesCynata have the funds or the skills in management to do anythingabout that?

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I won't ask those, yet, (I see the main game currently as taking place between MSB and the FDA over GvHD BLA or not sooner than sculptor results or CYP phase 2 results) - so others can have them for nothing if they want to ask tommorow



I do think shareholders should get Kilian on the record about GvHD stuff - but experience suggests they (except for pfeifer) they won't and I expect Kilian would prefer to keep things rubbery and non specific.