In modern times the most valuable research in terms of...

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    In modern times the most valuable research in terms of practicality was done with absolutely no sense of practicality.

    In other words pure science has lead to the most significant technological advances

    This type of research has generated the most wealth and is why funding NASA space exploration - at best the refinement of already existing technology - at the expense of research into how the universe works, such as fundamental particle research, has been a little known scandal of massive proportions.
 
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