https://www.news.com.au/lifestyle/health/health-problems/aussie-mum-moves-overseas-due-to-debilitating-skin-issue/news-story/61c5702b588701bd9a053b83a3461556
Predominant Role of mTOR Signaling in Skin Diseases with Therapeutic PotentialFani Karagianni et al,2023
States :
"In regard to protein synthesis, mTORC1 phosphorylates and inhibits the eukaryotic initiation factor binding proteins (4E-BPs), leading to eIF4E release and promoting mRNA translation [20]. Additionally, mTORC1 phosphorylates S6K1, which enhances translation by activating eIF4B and degrading eIF4A inhibitor-programmed cell death 4 (PDCD4) [21,22]. Moreover, mTORC1 and S6K1 enhance the transcription of rRNA by increasing RNA polymerase I and III activity, regulating ribosome biogenesis, and protein synthesis, thus contributing to regulation of cell mass"
Monepantel to my knowledge has the attributes to have an effect on certain skin diseases including eczema.
Kpax
https://www.news.com.au/lifestyle/health/health-problems/aussie-m...
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