it seems the exact manufacturing site is not publicly discloused.
From Acadia's last Annual Report
We have contracted with Corden Pharma Bergamo S.p.A.(Corden), to manufacture the API for trofinetide products.
We also have contracted with F.I.S. Fabbrica Italiana Sintetici S.p.A.(FIS) to manufacture the API for trofinetide products.
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