I really don’t know how important this would be.
I do know that Neuren filed an international patent application two years ago for new compositions and manufacturing methods which allow substantially larger quantities of trofinetide to be produced in a way that is more commercially beneficial.
The inventors listed on this patent are drawn from Neuren, Acadia and PeptiSyntha SA Belgium/ Corden Pharma Switzerland (Corden is the parent company of PeptiSyntha). So Corden is at least a conveniently located manufacturer for any European pharma.
Under the terms of the licence, Acadia was granted a non-exclusive licence to have trofinetide manufactured outside of North America.
https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2021026066&_cid=P11-L9FI68-39396-4
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