If we get to a high of 22 prior to readout and results turn out...

If we get to a high of 22 prior to readout and results turn out negative, I do see recent buyers (who bought at a premium) as eager to sell. There may be other loose hands who get caught by the red sentiment, so that the shareprice falls back down to 10. I also wouldn't blame long term holders for taking a bit of profit.

that said, the next sales and royalty update should level it back up to the levels we were stuck on for ages - 11, 12 or 13 dollars.

It will test the patience of long term holders, and i agree with baldwidx that we could infer negative results in 1 could lead to negative results in any of the other trials.

what are the chances of all 4 trials being negative though? Unlikely I think, after everything we've heard about 2591 being the superior chemical compound...

those who believe and hold on will be the ones that see a profit when the tide turns.