Share Price, page-25

Can I add - and correct me if I'm wrong - that Lilac enrolment's greatest allure was/is settling the question for the parents of whether or not their child was on the drug during the double blind phase (Lavender).

So going into Lilac you would have these sort of broad mindsets presumably:

1. I think my child was on the drug because I saw changes that I can't account for (and they were positive changes) and I want that to continue;
2. I'm not sure if my child was on the drug but I saw changes that were kind of positive, so I'd like to be sure by knowing we have the drug;
3. I'm sure my child was on placebo because nothing happened (or changed) so Lilac is really the start of the Trial as far as we are concerned.

IMO, group two and three would be the most motivated to get into Lilac to find out (once and for all).

Once again I have learnt from Hottod in that "by invitation" caveat. Wasn't aware of that. Who knows what that means or why that has come about - it may be as simple as weeding out families who did not reliably follow appointment times and protocols during Lavender, and it may be more than that.

So, the high enrolment in Lilac doesn't surprise. But not for the reason that the drug might be working - only group one would go in convinced one way or the other that that is the case. The enrolment in Lilac is only about certainty in receiving treatment. Lilac drop-out numbers would be far more telling.