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12:47
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Originally posted by windsurfar
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Oct 10 we had the Yervoy preliminary data release. The efficacy results exceeded my expectations, but the safety data was unexpected, in a very good way: no dose limiting toxicities in 17 patients treated with Yervoy/Cavatak combo. Only one grade 3 level fatigue as the only grade 3 or 4 toxicity!!! That just doesn't happen with the checkpoint inhibitors usually. It may be telling us of a truly outstanding benefit in that the viral infection could be redirecting the immune related activities against normal tissues that you normally see. One study i read had a 31% rate of grade 3 or 4 toxicities with Yervoy treatment.
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Hi
