This interesting, QuantiFERON ® -TB Gold In-Tube and Mycobacterium tuberculosisAntibody, IgG by ELISA FoR Use in the DiAgnosis oF lAtent oR Active MycobActeRiUM tUbeRcUlosis inFection Test Highlights New panel combines the QuantiFERON• ® -TB Gold in-tube test (QFT- GIT) with the Mtb IgG ELISA.Requires only a single patient visit to draw blood sample.• The nil tube required for the QuantiFERON• ® -TB Gold in-tube test provides plasma for use in the IgG ELISA, so no extra draw is required.Panel increases the ability to differentiate active and latent cases of TB.• Interpretation A positive QFT-GIT result indicates latent TB infection.• A positive IgG result indicates progression to active disease.• References Mandell G, Bennett J, Dolin R, eds. 2000. 1.Principles and Practice of infectious Diseases, 5th ed. New York: Churchill Livingston.Shi R, et al. Overview of anti-tuberculosis (TB) drugs 2.and their resistance mechanisms. Mini Rev Med chem2007;7(11):1177–85.Nyamande K, et al. TB presenting as community-aquired 3.pneumonia in a setting of high TB incidence and high HIVprevalence. int J tuberc lung Dis 2007;11(12):1308–13.Shinnick TM, et al. National plan for reliable tuberculosis 4.laboratory services using a systems approach. Recommendations from CDC and the Association of Public Health Laboratories Task Force on Tuberculosis Laboratory Services. MMWR Recomm Rep 2005;54(RR-6):1–12.Carvalho AC, et al. QuantiFERON®-TB Gold test in the 5.identification of latent tuberculosis infection in immigrants. J infect 2007;55(2):164–8.Mazuerk GH, et al. Guidelines for using the QuantiFERON®-6.TB Gold test for detecting Mycobacterium tuberculosis infection, United States. MMWR Recomm Rep2005;54:49–55.Active Tb7.Detect ™ Kit. Package Insert InBios, 2008. Page 2 ARUP LABORATORIES | MAY 2009 2001627QuantiFERON®-TB Gold In Tube & Mycobacterium tuberculosis Antibody, IgG For specific collection, transport, and testing information, refer to the ARUP Web site at www.aruplab.com.For information on test selection, ordering, and interpretation, refer to ARUP Consult ® at www.arupconsult.com. Test Information
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