Something has to change., page-120

Logzy, I don't know how many times I must tell you it is not the management it is the product. The fact are Ionis produced one gen 1 to market which failed being commercial viable after only 18 months. At this point only one Gen 2 made it to market in 2011 which has since been pulled. during the five years Kynamro was in the market Genzyme was to embarrassed to supply sales figures. Ionis is now on gen 2.5 with only about six products produced prior to 2011 two of which are ANP's. ANP completed phase 2 in 2009 for 1102 and phase 2 for 1103 in 2014, since then any further progress has been stalled.