OSL investors should not be fearful of competitors. Differing views from DrDopamine are most welcome. My searches have proven to be educational and I would like to share with HC members. The following differences between Angiodynamics' IRE Irreversible Electroporation (Nanoknife) product vs Oncosil are in red. In conclusion, I stand to be corrected. IMHO OSL appears to be far more superior than IRE! DYOR.

What is the NanoKnife procedure?

Since being introduced to US market in 2007, theNanoKnifeSystem has been used in over 5,450procedures. ANanoKnife*procedureis an ablationprocedurethat involves the delivery of a series of high voltage direct current electrical pulses between two electrodes placed within a target area of tissue.

More info:

The NanoKnife System - AngioDynamics

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640920/

Irreversible Electroporation

... ... ...

Pancreas

Narayanan et al reported aretrospective review of 43patients who underwent 50 IRE procedures using a percutaneous approach.¹⁹ (Fig. 4). Thirty out of 43 (69.8%) patients had LAPC, and the overall survival in these patients was 16.2 months (95% CI: 10.1–22.3 months). The remaining 13 patients (30.2%) had MPC, and had an overall survival of 8.6 months (95% CI: 3.1–14.1 months). Nineteen patients (44%) received chemotherapy after IRE. Two patients with LAPC were downstaged and were able toundergo surgery with R0 (margin negative) resections.

*** That's 2 resections outof 43 patients = 4.65% which is not fantastic at all when compared to OSL's23.8% (10 resections out of 42 patients). Data from ASX Announcement / Media Release 28 October 2019 - "OncoSil submits updated Clinical Evaluation Report to BSI" https://www.asx.com.au/asxpdf/20191028/pdf/449z6ryx66vvt8.pdf

In this series, the complications from pancreatic IRE included abdominalpain (n = 10), pancreatitis (n = 7), hematoma (n = 7),spontaneous pneumothorax (n = 1), the need for a duodenal stentplacement (n = 1), main portal vein thrombosis (found at 1 monthfollow-up CT scan) (n = 1), and sepsis 48 hours post-IRE (n = 1).Cases of pancreatitis were managed with an extended hospital stay andconservative management.

*** So many patientssuffered from post-op complications. In stark contrast with OSL, "There wereno complications reported immediately, 7 days, or 30 days after theimplantation. Treatment was well tolerated in all subjects with reduction inpain score". OSL's statement from the following PDF.

https://www.oncosil.com.au/static/uploads/files/bartholomeusz-d-2019-abs-anzsnm-wfehhrtosusr.pdf