Roche signed a deal with Aileron last year to investigate stapled peptides. as below. from http://blog.pharmtech.com/2010/08/31/roche?s-1-billion-bet-on-stapled-peptides/ Dont know if phyligica get any benefit through their collaboration with Roche. Wonder if they can produce a peptide from the phylomer library that can be stapled, and have an extended half life due to the collaboration with XL protein GMBH. That could be a winner?
Roche (Basel, Switzerland) announced last week that it signed a drug-development deal worth up to $1.1 billion with the biopharmaceutical company Aileron Therapeutics (Cambridge, MA) to discover, develop, and commercialize ?stapled peptides,? or drug candidates that use peptide-stabilization technology to enhance potency and cell permeability. So are stapled peptides a potential magic bullet in biopharmaceutical development?
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