Another recent publication with Novosorb BTM receiving extra mention
7. Complex Coverage Options
Dorsal hand structures can quickly become exposed and are prone to desiccation
and further injury due to the relatively thin skin and subcutaneous tissue. When a donor
autograft must be used for lifesaving wound coverage over other areas of the body, or there
are exposed tendons or other structures, standard STSG use may not be an initial option. In
this setting, dermal substitutes/matrices can be used to protect the underlying structures to
provide a vascularized dermal replacement and to create a more robust wound bed for later
autograft application. There are several dermal substitutes available [30–32], including
dermal regeneration templates (e.g., Integra bilayer wound matrix; Integra Life Sciences,
Plainsboro, NJ, USA) and acellular dermal matrices (e.g., Matriderm; Medskin Solutions
Dr. Suwelack AG, Billerbeck, Germany and NovoSorb® Biodegradable Temporising Matrix
(BTM) and PolyNovo Biomaterials Pty Ltd., Port Melbourne, Victoria, Australia). Typically,
use of these products requires a staged approach: excision and placement of dermal product
at the first operation; engraftment of product during a 2–3-week period; and autografting
at the second operation. Successful use requires that the wound bed be sterile and free of
devitalized tissue. This may not be possible in a battlefield setting. Data from a multi-center,
prospective, clinical trial suggest that when managed appropriately, the BTM performs in a
relatively robust manner even in the presence of infection [33].
https://mdpi-res.com/d_attachment/ebj/ebj-05-00011/article_deploy/ebj-05-00011.pdf?version=1714918858
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