CYP cynata therapeutics limited

The Phase I/IIb Nereid Study Is Now Registered, page-4

  1. 1,315 Posts.
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    Blue bit:

    https://hotcopper.com.au/data/attachments/6025/6025824-7e19b4810fcaeb7c177f2ae0b2221462.jpg
    https://www.nature.com/articles/s41591-020-1050-x

    Yellow bit:

    Dr Temple during the ODAC meeting 2020:
    https://hotcopper.com.au/data/attachments/6025/6025827-83abb099be8872905e4fe40e01fc0f6a.jpg
    https://hotcopper.com.au/data/attachments/6025/6025829-bd91a5bf4804e01a202b3ea22bfae7a0.jpg
    https://web.archive.org/web/20210305082200/https://www.fda.gov/media/143337/download

    Essentially, you have a manufacturing process for your MSC-therapy, that could result in one specific product today which could result in a complete response, partial response or no response today, could result in a different outcome if the same manufacturing process is used a week later after an additional round of medications, or a year later due to age, or the same day depending on the origin of the MSCs (despite them all being MSCs). More information can also be found here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10453316/

    Now with Cymerus you potentially have a process from start to end that could eliminate all these confounding factors, since the starting material will remain the same (cryo-preservation perhaps is something that should be closer looked into), and the manufacturing process also remains the same, today, tomorrow, next year, which makes it attractive in the eyes of Hunter, LUMC etc.
    Last edited by pfeifer1982: 12/03/24
 
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