I'm sure I've read this before. I've specifically wondered about the passage "While vaccine-induced antibody responses were not detectable, cell-mediated immune responses to HSV-specific peptide groups were identified in 19 of the 20 subjects who completed the study, and local inflammation at the immunisation site was observed". It appears the vaccine does what it says on the tin. No antibody response, but results in cell-mediated immunity re: wikipedia: "Cell-mediated immunity is an immune response that does not involve antibodies, but rather involves the activation of phagocytes, antigen-specific cytotoxic T-lymphocytes, and the release of various cytokines in response to an antigen."
https://en.wikipedia.org/wiki/Cell-mediated_immunity
Hopefully, this translates to real world outcomes for people in the current trial.
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